ABSTRACT
Objetivo: Determinar a incidência de retinopatia daprematuridade (ROP) no Hospital Universitário (HU) da UniversidadeFederal de Santa Catarina (UFSC) entre 2010 e2011, correlacionando-a com peso ao nascimento, idadegestacional e uso de oxigênio. Métodos: Entre os 1813nascidos vivos no período de abril de 2010 a março de2011 na maternidade do HU da UFSC, foram examinados33 prematuros com peso <1.500g e/ou idade gestacional<32 semanas. O mapeamento de retina foi realizado inicialmenteentre 4 e 6 semanas de vida e repetido a cada 1 a2 semanas. Para análise estatística, considerou-se a retinopatiamais grave que o recém-nascido (RN) apresentou nasua evolução. Os fatores de risco avaliados foram o peso aonascimento, a idade gestacional e o uso de oxigênio. Resultados:A incidência da doença entre o total de RNs foi de0,7%. Entre os recém-nascidos incluídos no protocolo parao exame oftalmológico, 33 sobreviveram durante o estudoe realizaram o acompanhamento corretamente, sendo quedestes 42,4% desenvolveram ROP: 85,71% apresentaramgrau 1 de ROP. Apenas um paciente apresentou estágio 3(7,3%) da doença e um paciente estágio 4 (7,3%), os quaisforam os únicos (14,2%) tratados. Os fatores de risco estudadosmostraram associação com o desenvolvimento dadoença, mostrando significância estatística quando aplicadosao teste Mann-Whitney. Conclusão: A incidência deROP se mostrou semelhante a encontrada em importantesestudos realizados em países desenvolvidos. No entanto,recomendamos um estudo mais abrangente na mesma instituiçãoa fim de complementar este trabalho.
Objectives: Determinate the incidence of Retinopathyof Prematurity (ROP) at The Hospital of the FederalUniversity of Santa Catarina (UFSC) from 2010 to 2011,correlating with the birth weight, gestational age anduse of oxygen. Methods: Among the 1813 born alivebetween April 2010 and March 2011 in the maternityof the UFSC University Hospital, 33 examinations wereconducted on neonates with birth weight <1.500g and/or gestational age <32 weeks. The mapping of the retinawas first conducted between 4th and the 6th weekof life and it was repeated after 1 to 2 weeks. The surveywas conducted according to the Brazilian GuidelinesProposal for ROP. For the purposes of statisticalanalysis, the most serious phase of ROP presented bythe neonate was considered. The risk factors consideredfor the study were the birth weight, gestational ageand use of oxygen. Results: The incidence of ROP was0,7% among all neonates. During the study, 33 babiessurvived and followed up the examinations, and amongthis group 14 children (42,4%) presented ROP: Fromthem 85,7% showed ROP 1. One infant developed thedisease up to stage 3 (7,3%) and one progressed tothe 4th stage (7,3%). These two infants (14,2%) weretreated. The risk factors studied were associated to thedisease development showing significant statistic whenMann ?Whitney test was applied. Conclusion: The incidences of ROP in this study showedresemblance to those found in important studiesrealized in developed countries, but its recommendeda more embracing study in the same institution to complementthis essay.
ABSTRACT
In order to mark Triatoma brasiliensis, the vector of Chagas disease in Brazil, two chemical compounds, rubidium chloride (RbCl) and chromium chloride (CrCl3), were tested. First, 199 N2-N5 nymphs were fed on blood with 0.025M RbCl. Rb marker positivity ranged from 2.5 percent (N3)-70 percent (N2), with a maximum persistence of 98 days. Second, 265 N2-N5 nymphs were fed on blood containing 0.0015M CrCl3. Cr marker positivity ranged up to 93 percent (N5), with a maximum persistence of 119 days. Finally, we blood fed 213 T. brasiliensis to investigate whether CrCl3 altered the biology of this insect. The developmental time of T. brasiliensis was unaltered, but the survival of the Cr-marked group was lower than that of the control group. Differences in the mean fecundity of the control (mean of 156.1) and experimental (mean of 135.6) groups were not statistically significant and 100 percent of the egg batches of females Cr-marked as nymphs were positive. In conclusion, CrCl3 is a useful tool for marking T. brasiliensis nymphs due to its high positivity and persistence.